Sour Mash is the best known mash and is the method used to make bourbon and Tennessee whiskey. In this method a small amount of already fermented mash (now sour) is held from the previous fermentation and used in the following batch, thus continuing the quality in yeast used.
Sweet Mash on the other hand uses fresh yeast which fermented in open-topped vats before being distilled giving a fresh, sweet flavor as opposed to sour.

